Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells

Covalent modification of DNA distinguishes cellular identities and is crucial for regulating the pluripotency and differentiation of embryonic stem (ES) cells. The recent demonstration that 5-methylcytosine (5-mC) may be further modified to 5-hydroxymethylcytosine (5-hmC) in ES cells has revealed a...

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Autores principales: Szulwach, Keith E., Li, Xuekun, Li, Yujing, Song, Chun-Xiao, Han, Ji Woong, Kim, SangSung, Namburi, Sandeep, Hermetz, Karen, Kim, Julie J., Rudd, M. Katharine, Yoon, Young-Sup, Ren, Bing, He, Chuan, Jin, Peng
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121778/
https://ncbi.nlm.nih.gov/pubmed/21731508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002154
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