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Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome
The study of 5-hydroxylmethylcytosines (5hmC) has been hampered by the lack of a method to map it at single-base resolution on a genome-wide scale. Affinity purification-based methods cannot precisely locate 5hmC nor accurately determine its relative abundance at each modified site. We here present...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3589129/ https://ncbi.nlm.nih.gov/pubmed/22608086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.04.027 |
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