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Epigenomic landscape of 5-hydroxymethylcytosine reveals its transcriptional regulation of lncRNAs in colorectal cancer

BACKGROUND: DNA methylation at the 5 position of cytosine (5mC) can be converted to 5-hydroxymethylcytosine (5hmC) by the ten–eleven translocation family. The loss of global levels of 5hmC has been regarded as a hallmark in various cancers. 5-hydroxymethylcytosine is distributed at protein-coding ge...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Hu, Hanyang, Shu, Maoguo, He, Lin, Yu, Xueyuan, Liu, Xiangyu, Lu, Yalin, Chen, Yinghong, Miao, Xiaoping, Chen, Xiaohua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344292/
https://ncbi.nlm.nih.gov/pubmed/28141796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.457
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