Efficacy of the Investigational Antifungal VT-1161 in Treating Naturally Occurring Coccidioidomycosis in Dogs

Por Shubitz, Lisa F., Roy, Michael E., Trinh, Hien T., Hoekstra, William J., Schotzinger, Robert J., Garvey, Edward P.
Publicado no Antimicrob Agents Chemother (2017)

VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection

Por Gebremariam, Teclegiorgis, Wiederhold, Nathan P., Fothergill, Annette W., Garvey, Edward P., Hoekstra, William J., Schotzinger, Robert J., Patterson, Thomas F., Filler, Scott G., Ibrahim, Ashraf S.
Publicado no Antimicrob Agents Chemother (2015)

The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme

Por Warrilow, Andrew G. S., Parker, Josie E., Price, Claire L., Nes, W. David, Garvey, Edward P., Hoekstra, William J., Schotzinger, Robert J., Kelly, Diane E., Kelly, Steven L.
Publicado no Antimicrob Agents Chemother (2016)

Pharmacovirological Impact of an Integrase Inhibitor on Human Immunodeficiency Virus Type 1 cDNA Species In Vivo

Por Goffinet, Christine, Allespach, Ina, Oberbremer, Lena, Golden, Pamela L., Foster, Scott A., Johns, Brian A., Weatherhead, Jason G., Novick, Steven J., Chiswell, Karen E., Garvey, Edward P., Keppler, Oliver T.
Publicado em 2009

The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii

Por Lockhart, Shawn R., Fothergill, Annette W., Iqbal, Naureen, Bolden, Carol B., Grossman, Nina T., Garvey, Edward P., Brand, Stephen R., Hoekstra, William J., Schotzinger, Robert J., Ottinger, Elizabeth, Patterson, Thomas F., Wiederhold, Nathan P.
Publicado no Antimicrob Agents Chemother (2016)

Antiviral Characteristics of GSK1265744, an HIV Integrase Inhibitor Dosed Orally or by Long-Acting Injection

Por Yoshinaga, Tomokazu, Kobayashi, Masanori, Seki, Takahiro, Miki, Shigeru, Wakasa-Morimoto, Chiaki, Suyama-Kagitani, Akemi, Kawauchi-Miki, Shinobu, Taishi, Teruhiko, Kawasuji, Takashi, Johns, Brian A., Underwood, Mark R., Garvey, Edward P., Sato, Akihiko, Fujiwara, Tamio
Publicado no Antimicrob Agents Chemother (2014)

Identification of Peptides That Inhibit the DNA Binding, trans-Activator, and DNA Replication Functions of the Human Papillomavirus Type 11 E2 Protein

Por Deng, Su-Jun, Pearce, Kenneth H., Dixon, Eric P., Hartley, Kelly A., Stanley, Thomas B., Lobe, David C., Garvey, Edward P., Kost, Thomas A., Petty, Regina L., Rocque, Warren J., Alexander, Kenneth A., Underwood, Mark R.
Publicado em 2004

Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models

Por Shubitz, Lisa F., Trinh, Hien T., Galgiani, John N., Lewis, Maria L., Fothergill, Annette W., Wiederhold, Nathan P., Barker, Bridget M., Lewis, Eric R. G., Doyle, Adina L., Hoekstra, William J., Schotzinger, Robert J., Garvey, Edward P.
Publicado no Antimicrob Agents Chemother (2015)

In Vitro Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor

Por Kobayashi, Masanori, Yoshinaga, Tomokazu, Seki, Takahiro, Wakasa-Morimoto, Chiaki, Brown, Kevin W., Ferris, Robert, Foster, Scott A., Hazen, Richard J., Miki, Shigeru, Suyama-Kagitani, Akemi, Kawauchi-Miki, Shinobu, Taishi, Teruhiko, Kawasuji, Takashi, Johns, Brian A., Underwood, Mark R., Garvey, Edward P., Sato, Akihiko, Fujiwara, Tamio
Publicado em 2011

The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

Por Garvey, Edward P., Johns, Brian A., Gartland, Margaret J., Foster, Scott A., Miller, Wayne H., Ferris, Robert G., Hazen, Richard J., Underwood, Mark R., Boros, Eric E., Thompson, James B., Weatherhead, Jason G., Koble, Cecilia S., Allen, Scott H., Schaller, Lee T., Sherrill, Ronald G., Yoshinaga, Tomokazu, Kobayashi, Masanori, Wakasa-Morimoto, Chiaki, Miki, Shigeru, Nakahara, Koichiro, Noshi, Takeshi, Sato, Akihiko, Fujiwara, Tamio
Publicado em 2008

The Naphthyridinone GSK364735 Is a Novel, Potent Human Immunodeficiency Virus Type 1 Integrase Inhibitor and Antiretroviral

Por Garvey, Edward P., Johns, Brian A., Gartland, Margaret J., Foster, Scott A., Miller, Wayne H., Ferris, Robert G., Hazen, Richard J., Underwood, Mark R., Boros, Eric E., Thompson, James B., Weatherhead, Jason G., Koble, Cecilia S., Allen, Scott H., Schaller, Lee T., Sherrill, Ronald G., Yoshinaga, Tomokazu, Kobayashi, Masanori, Wakasa-Morimoto, Chiaki, Miki, Shigeru, Nakahara, Koichiro, Noshi, Takeshi, Sato, Akihiko, Fujiwara, Tamio
Publicado em 2008