The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii

The in vitro activities of the novel fungal Cyp51 inhibitor VT-1129 were evaluated against a large panel of Cryptococcus neoformans and Cryptococcus gattii isolates. VT-1129 demonstrated potent activities against both Cryptococcus species as demonstrated by low MIC(50) and MIC(90) values. For C. gat...

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發表在:Antimicrob Agents Chemother
Main Authors: Lockhart, Shawn R., Fothergill, Annette W., Iqbal, Naureen, Bolden, Carol B., Grossman, Nina T., Garvey, Edward P., Brand, Stephen R., Hoekstra, William J., Schotzinger, Robert J., Ottinger, Elizabeth, Patterson, Thomas F., Wiederhold, Nathan P.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
主題:
Susceptibility
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808209/
https://ncbi.nlm.nih.gov/pubmed/26787697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02770-15
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