The Investigational Fungal Cyp51 Inhibitor VT-1129 Demonstrates Potent In Vitro Activity against Cryptococcus neoformans and Cryptococcus gattii

The in vitro activities of the novel fungal Cyp51 inhibitor VT-1129 were evaluated against a large panel of Cryptococcus neoformans and Cryptococcus gattii isolates. VT-1129 demonstrated potent activities against both Cryptococcus species as demonstrated by low MIC(50) and MIC(90) values. For C. gat...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Lockhart, Shawn R., Fothergill, Annette W., Iqbal, Naureen, Bolden, Carol B., Grossman, Nina T., Garvey, Edward P., Brand, Stephen R., Hoekstra, William J., Schotzinger, Robert J., Ottinger, Elizabeth, Patterson, Thomas F., Wiederhold, Nathan P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808209/
https://ncbi.nlm.nih.gov/pubmed/26787697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02770-15
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