In Vitro Antiretroviral Properties of S/GSK1349572, a Next-Generation HIV Integrase Inhibitor

S/GSK1349572 is a next-generation HIV integrase (IN) inhibitor designed to deliver potent antiviral activity with a low-milligram once-daily dose requiring no pharmacokinetic (PK) booster. In addition, S/GSK1349572 demonstrates activity against clinically relevant IN mutant viruses and has potential...

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Detalhes bibliográficos
Main Authors: Kobayashi, Masanori, Yoshinaga, Tomokazu, Seki, Takahiro, Wakasa-Morimoto, Chiaki, Brown, Kevin W., Ferris, Robert, Foster, Scott A., Hazen, Richard J., Miki, Shigeru, Suyama-Kagitani, Akemi, Kawauchi-Miki, Shinobu, Taishi, Teruhiko, Kawasuji, Takashi, Johns, Brian A., Underwood, Mark R., Garvey, Edward P., Sato, Akihiko, Fujiwara, Tamio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3028777/
https://ncbi.nlm.nih.gov/pubmed/21115794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01209-10
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