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Barrier to Resistance of Dolutegravir in Two-Drug Combinations

A major concern when using two-drug anti-HIV regimens is the risk of viral resistance. However, no techniques to evaluate the barrier to resistance of two-drug combinations in vitro have been reported. We evaluated the emergence of drug-resistant mutants in a passage study with constant concentratio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Yoshinaga, Tomokazu, Miki, Shigeru, Kawauchi-Miki, Shinobu, Seki, Takahiro, Fujiwara, Tamio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6395897/
https://ncbi.nlm.nih.gov/pubmed/30602514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02104-18
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