Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models

Coccidioidomycosis, or valley fever, is a growing health concern endemic to the southwestern United States. Safer, more effective, and more easily administered drugs are needed especially for severe, chronic, or unresponsive infections. The novel fungal CYP51 inhibitor VT-1161 demonstrated in vitro...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Shubitz, Lisa F., Trinh, Hien T., Galgiani, John N., Lewis, Maria L., Fothergill, Annette W., Wiederhold, Nathan P., Barker, Bridget M., Lewis, Eric R. G., Doyle, Adina L., Hoekstra, William J., Schotzinger, Robert J., Garvey, Edward P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649211/
https://ncbi.nlm.nih.gov/pubmed/26369964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00593-15
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