Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models

Coccidioidomycosis, or valley fever, is a growing health concern endemic to the southwestern United States. Safer, more effective, and more easily administered drugs are needed especially for severe, chronic, or unresponsive infections. The novel fungal CYP51 inhibitor VT-1161 demonstrated in vitro...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Shubitz, Lisa F., Trinh, Hien T., Galgiani, John N., Lewis, Maria L., Fothergill, Annette W., Wiederhold, Nathan P., Barker, Bridget M., Lewis, Eric R. G., Doyle, Adina L., Hoekstra, William J., Schotzinger, Robert J., Garvey, Edward P.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Experimental Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649211/
https://ncbi.nlm.nih.gov/pubmed/26369964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00593-15
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