VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection

We studied the efficacy of the investigational drug VT-1161 against mucormycosis. VT-1161 had more potent in vitro activity against Rhizopus arrhizus var. arrhizus than against R. arrhizus var. delemar. VT-1161 treatment demonstrated dose-dependent plasma drug levels with prolonged survival time and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Gebremariam, Teclegiorgis, Wiederhold, Nathan P., Fothergill, Annette W., Garvey, Edward P., Hoekstra, William J., Schotzinger, Robert J., Patterson, Thomas F., Filler, Scott G., Ibrahim, Ashraf S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Experimental Therapeutics
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649228/
https://ncbi.nlm.nih.gov/pubmed/26369977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01437-15
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia