Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus

Mucormycosis is a life-threatening infection with high mortality that occurs predominantly in immunocompromised patients. Manogepix (MGX) is a novel antifungal that targets Gwt1, a protein involved in an early step in the conserved glycosylphosphotidyl inositol (GPI) posttranslational modification p...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Gebremariam, Teclegiorgis, Alkhazraji, Sondus, Alqarihi, Abdullah, Wiederhold, Nathan P., Shaw, Karen Joy, Patterson, Thomas F., Filler, Scott G., Ibrahim, Ashraf S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269494/
https://ncbi.nlm.nih.gov/pubmed/32205345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00178-20
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky