APX001A Protects Immunosuppressed Mice from Rhizopus delemar Infection

BACKGROUND: Mucormycosis is a life-threatening infection with high mortality that occurs predominantly in immunocompromised patients. APX001A is an antifungal agent that targets Gwt1, an early step in the conserved glycosylphosphotidyl inositol (GPI) post-translational modification pathway of surfac...

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Publicado en:Open Forum Infect Dis
Main Authors: Gebremariam, Teclegiorgis, Alkhazraji, Sondus, Alqarihi, Abdullah, Wiederhold, Nathan P, Shaw, Karen Joy, Patterson, Thomas F, Filler, Scott, Ibrahim, Ashraf
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630889/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1217
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