APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis

Invasive pulmonary aspergillosis (IPA) due to Aspergillus fumigatus is a serious fungal infection in the immunosuppressed patient population. Despite the introduction of new antifungal agents, mortality rates remain high, and new treatments are needed. The novel antifungal APX001A targets the conser...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Gebremariam, Teclegiorgis, Alkhazraji, Sondus, Alqarihi, Abdullah, Jeon, Heewon H., Gu, Yiyou, Kapoor, Mili, Shaw, Karen J., Ibrahim, Ashraf S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355556/
https://ncbi.nlm.nih.gov/pubmed/30455236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01713-18
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