Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis

There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium. Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of glycosylphosphatidylinositol-anchored mannopro...

詳細記述

保存先:
書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Alkhazraji, Sondus, Gebremariam, Teclegiorgis, Alqarihi, Abdullah, Gu, Yiyou, Mamouei, Zeinab, Singh, Shakti, Wiederhold, Nathan P., Shaw, Karen J., Ibrahim, Ashraf S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2020
主題:
Experimental Therapeutics
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038288/
https://ncbi.nlm.nih.gov/pubmed/31818813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01735-19
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料