Fosmanogepix (APX001) Is Effective in the Treatment of Immunocompromised Mice Infected with Invasive Pulmonary Scedosporiosis or Disseminated Fusariosis

There are limited treatment options for immunosuppressed patients with lethal invasive fungal infections due to Fusarium and Scedosporium. Manogepix (MGX; APX001A) is a novel antifungal that targets the conserved Gwt1 enzyme required for localization of glycosylphosphatidylinositol-anchored mannopro...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Alkhazraji, Sondus, Gebremariam, Teclegiorgis, Alqarihi, Abdullah, Gu, Yiyou, Mamouei, Zeinab, Singh, Shakti, Wiederhold, Nathan P., Shaw, Karen J., Ibrahim, Ashraf S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2020
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038288/
https://ncbi.nlm.nih.gov/pubmed/31818813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01735-19
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