Fosmanogepix (APX001) Is Effective in the Treatment of Pulmonary Murine Mucormycosis Due to Rhizopus arrhizus

Mucormycosis is a life-threatening infection with high mortality that occurs predominantly in immunocompromised patients. Manogepix (MGX) is a novel antifungal that targets Gwt1, a protein involved in an early step in the conserved glycosylphosphotidyl inositol (GPI) posttranslational modification p...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Gebremariam, Teclegiorgis, Alkhazraji, Sondus, Alqarihi, Abdullah, Wiederhold, Nathan P., Shaw, Karen Joy, Patterson, Thomas F., Filler, Scott G., Ibrahim, Ashraf S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2020
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269494/
https://ncbi.nlm.nih.gov/pubmed/32205345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00178-20
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