In Vitro Activities of the Novel Investigational Tetrazoles VT-1161 and VT-1598 Compared to the Triazole Antifungals against Azole-Resistant Strains and Clinical Isolates of Candida albicans

The fungal Cyp51-specific inhibitors VT-1161 and VT-1598 have emerged as promising new therapies to combat fungal infections, including Candida spp. To evaluate their in vitro activities compared to other azoles, MICs were determined by Clinical and Laboratory Standards Institute (CLSI) method for V...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Nishimoto, Andrew T., Wiederhold, Nathan P., Flowers, Stephanie A., Zhang, Qing, Kelly, Steven L., Morschhäuser, Joachim, Yates, Christopher M., Hoekstra, William J., Schotzinger, Robert J., Garvey, Edward P., Rogers, P. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535515/
https://ncbi.nlm.nih.gov/pubmed/30910896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00341-19
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