In Vitro Activities of the Novel Investigational Tetrazoles VT-1161 and VT-1598 Compared to the Triazole Antifungals against Azole-Resistant Strains and Clinical Isolates of Candida albicans

The fungal Cyp51-specific inhibitors VT-1161 and VT-1598 have emerged as promising new therapies to combat fungal infections, including Candida spp. To evaluate their in vitro activities compared to other azoles, MICs were determined by Clinical and Laboratory Standards Institute (CLSI) method for V...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Nishimoto, Andrew T., Wiederhold, Nathan P., Flowers, Stephanie A., Zhang, Qing, Kelly, Steven L., Morschhäuser, Joachim, Yates, Christopher M., Hoekstra, William J., Schotzinger, Robert J., Garvey, Edward P., Rogers, P. David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535515/
https://ncbi.nlm.nih.gov/pubmed/30910896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00341-19
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