Impact of the Major Candida glabrata Triazole Resistance Determinants on the Activity of the Novel Investigational Tetrazoles VT-1598 and VT-1161

VT-1161 and VT-1598 are promising investigational tetrazole antifungals that have shown in vitro and in vivo activity against Candida and other fungi. Candida glabrata is a problematic opportunistic pathogen that is associated with high mortality in invasive infection, as well as both intrinsic and...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Nishimoto, Andrew T., Whaley, Sarah G., Wiederhold, Nathan P., Zhang, Qing, Yates, Christopher M., Hoekstra, William J., Schotzinger, Robert J., Garvey, Edward P., Rogers, P. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761532/
https://ncbi.nlm.nih.gov/pubmed/31383660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01304-19
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