Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models

Coccidioidomycosis, or valley fever, is a growing health concern endemic to the southwestern United States. Safer, more effective, and more easily administered drugs are needed especially for severe, chronic, or unresponsive infections. The novel fungal CYP51 inhibitor VT-1161 demonstrated in vitro...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Shubitz, Lisa F., Trinh, Hien T., Galgiani, John N., Lewis, Maria L., Fothergill, Annette W., Wiederhold, Nathan P., Barker, Bridget M., Lewis, Eric R. G., Doyle, Adina L., Hoekstra, William J., Schotzinger, Robert J., Garvey, Edward P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649211/
https://ncbi.nlm.nih.gov/pubmed/26369964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00593-15
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