Tonic Dopamine Inhibition of L-Type Ca(2+) Channel Activity Reduces α(1D) Ca(2+) Channel Gene Expression

door Fass, Daniel M., Takimoto, Koichi, Mains, Richard E., Levitan, Edwin S.
Gepubliceerd in J Neurosci (1999)

Epigenetic Mechanisms in Mood Disorders: Targeting Neuroplasticity

door Fass, Daniel M., Schroeder, Frederick A., Perlis, Roy H., Haggarty, Stephen J.
Gepubliceerd in 2013

Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening

door Cheng, Chialin, Fass, Daniel M., Folz-Donahue, Kat, MacDonald, Marcy E., Haggarty, Stephen J.
Gepubliceerd in Curr Protoc Hum Genet (2017)

Kinetic Tuning of HDAC Inhibitors Affords Potent Inducers of Progranulin Expression

door Moreno-Yruela, Carlos, Fass, Daniel M., Cheng, Chialin, Herz, Joachim, Olsen, Christian A., Haggarty, Stephen J.
Gepubliceerd in ACS Chem Neurosci (2019)

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

door Kilgore, Mark, Miller, Courtney A, Fass, Daniel M, Hennig, Krista M, Haggarty, Stephen J, Sweatt, J David, Rumbaugh, Gavin
Gepubliceerd in 2010

Regulation of Primitive Hematopoiesis by Class I Histone Deacetylases

door Shah, Rishita R., Koniski, Anne, Shinde, Mansi, Blythe, Shelby A., Fass, Daniel M., Haggarty, Stephen J., Palis, James, Klein, Peter S.
Gepubliceerd in 2013

Dissecting Structure-Activity-Relationships of Crebinostat: Brain Penetrant HDAC Inhibitors for Neuroepigenetic Regulation

door Ghosh, Balaram, Zhao, Wen-Ning, Reis, Surya A., Patnaik, Debasis, Fass, Daniel M., Tsai, Li-Huei, Mazitschek, Ralph, Haggarty, Stephen J.
Gepubliceerd in Bioorg Med Chem Lett (2016)

Recruitment of CREB Binding Protein Is Sufficient for CREB-Mediated Gene Activation

door Cardinaux, Jean-Rene, Notis, John C., Zhang, Qinghong, Vo, Ngan, Craig, Johanna C., Fass, Daniel M., Brennan, Richard G., Goodman, Richard H.
Gepubliceerd in 2000

The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells

door Wilson, Andrew J, Holson, Edward, Wagner, Florence, Zhang, Yan-Ling, Fass, Daniel M, Haggarty, Stephen J, Bhaskara, Srividya, Hiebert, Scott W, Schreiber, Stuart L, Khabele, Dineo
Gepubliceerd in 2011

Automated structure–activity relationship mining: connecting chemical structure to biological profiles

door Wawer, Mathias J., Jaramillo, David E., Dancik, Vlado, Fass, Daniel M., Haggarty, Stephen J., Shamji, Alykhan F., Wagner, Bridget K., Schreiber, Stuart L., Clemons, Paul A.
Gepubliceerd in J Biomol Screen (2014)

Short-Chain HDAC Inhibitors Differentially Affect Vertebrate Development and Neuronal Chromatin

door Fass, Daniel M., Shah, Rishita, Ghosh, Balaram, Hennig, Krista, Norton, Stephanie, Zhao, Wen-Ning, Reis, Surya A., Klein, Peter S., Mazitschek, Ralph, Maglathlin, Rebecca L., Lewis, Timothy A., Haggarty, Stephen J.
Gepubliceerd in 2010

Dysregulation of miR-34a Links Neuronal Development to Genetic Risk Factors for Bipolar Disorder

door Bavamian, Sabine, Mellios, Nikolaos, Lalonde, Jasmin, Fass, Daniel M., Wang, Jennifer, Sheridan, Steven D., Madison, Jon M., Zhou, Fen, Rueckert, Erroll H., Barker, Doug, Perlis, Roy H., Sur, Mriganka, Haggarty, Stephen J.
Gepubliceerd in Mol Psychiatry (2015)

WNT/β-Catenin Pathway and Epigenetic Mechanisms Regulate the Pitt-Hopkins Syndrome and Schizophrenia Risk Gene TCF4

door Hennig, Krista M., Fass, Daniel M., Zhao, Wen-Ning, Sheridan, Steven D., Fu, Ting, Erdin, Serkan, Stortchevoi, Alexei, Lucente, Diane, Cody, Jannine D., Sweetser, David, Gusella, James F., Talkowski, Michael E., Haggarty, Stephen J.
Gepubliceerd in Mol Neuropsychiatry (2017)

Chemical-Genetic Screen Identifies Riluzole as an Enhancer of Wnt/β-catenin signaling in Melanoma

door Biechele, Travis L., Camp, Nathan D., Fass, Daniel M., Kulikauskas, Rima M., Robin, Nick C., White, Bryan D., Taraska, Corinne M., Moore, Erin C., Muster, Jeanot, Karmacharya, Rakesh, Haggarty, Stephen J., Chien, Andy J., Moon, Randall T.
Gepubliceerd in 2010

Histone deacetylase knockouts modify transcription, CAG instability and nuclear pathology in Huntington disease mice

door Kovalenko, Marina, Erdin, Serkan, Andrew, Marissa A, St Claire, Jason, Shaughnessey, Melissa, Hubert, Leroy, Neto, João Luís, Stortchevoi, Alexei, Fass, Daniel M, Mouro Pinto, Ricardo, Haggarty, Stephen J, Wilson, John H, Talkowski, Michael E, Wheeler, Vanessa C
Gepubliceerd in eLife (2020)

Functional Analysis of Rare Variants Found in Schizophrenia Implicates a Critical Role for GIT1-PAK3 Signaling in Neuroplasticity

door Kim, Myung Jong, Biag, Jonathan, Fass, Daniel M., Lewis, Michael C., Zhang, Qiangge, Fleishman, Morgan, Gangwar, Shanti Pal, Machius, Mischa, Fromer, Menachem, Purcell, Shaun M., McCarroll, Steven A., Rudenko, Gabby, Premont, Richard T., Scolnick, Edward M., Haggarty, Stephen J.
Gepubliceerd in Mol Psychiatry (2016)

Bruton’s Tyrosine Kinase Revealed as a Negative Regulator of Wnt–β-Catenin Signaling

door James, Richard G., Biechele, Travis L., Conrad, William H., Camp, Nathan D., Fass, Daniel M., Major, Michael B., Sommer, Karen, Yi, XianHua, Roberts, Brian S., Cleary, Michele A., Arthur, William T., MacCoss, Michael, Rawlings, David J., Haggarty, Stephen J., Moon, Randall T.
Gepubliceerd in Sci Signal (2009)

An epigenetic blockade of cognitive functions in the neurodegenerating brain

door Gräff, Johannes, Rei, Damien, Guan, Ji-Song, Wang, Wen-Yuan, Seo, Jinsoo, Hennig, Krista M., Nieland, Thomas J.F., Fass, Daniel M., Kao, Patricia F., Kahn, Martin, Su, Susan C., Samiei, Alireza, Joseph, Nadine, Haggarty, Stephen J., Delalle, Ivana, Tsai, Li-Huei
Gepubliceerd in 2012

Crebinostat: A Novel Cognitive Enhancer that Inhibits Histone Deacetylase Activity and Modulates Chromatin-Mediated Neuroplasticity

door Fass, Daniel M., Reis, Surya A., Ghosh, Balaram, Hennig, Krista M., Joseph, Nadine F., Zhao, Wen-Ning, Nieland, Thomas J.F., Guan, Ji-Song, Kuhnle, Chelsea E. Groves, Tang, Weiping, Barker, Douglas D., Mazitschek, Ralph, Schreiber, Stuart L., Tsai, Li-Huei, Haggarty, Stephen J.
Gepubliceerd in 2012

A Selective HDAC 1/2 Inhibitor Modulates Chromatin and Gene Expression in Brain and Alters Mouse Behavior in Two Mood-Related Tests

door Schroeder, Frederick A., Lewis, Michael C., Fass, Daniel M., Wagner, Florence F., Zhang, Yan-Ling, Hennig, Krista M., Gale, Jennifer, Zhao, Wen-Ning, Reis, Surya, Barker, Douglas D., Berry-Scott, Erin, Kim, Sung Won, Clore, Elizabeth L., Hooker, Jacob M., Holson, Edward B., Haggarty, Stephen J., Petryshen, Tracey L.
Gepubliceerd in 2013