Modular Architecture of the Hexameric Human Mitochondrial DNA Helicase

door Ziebarth, Tawn D., Farr, Carol L., Kaguni, Laurie S.
Gepubliceerd in 2007

Physiological and Biochemical Defects in Carboxyl-terminal Mutants of Mitochondrial DNA Helicase

door Matsushima, Yuichi, Farr, Carol L., Fan, Li, Kaguni, Laurie S.
Gepubliceerd in 2008

Drosophila melanogaster as a Model System to Study Mitochondrial Biology

door Fernández-Moreno, Miguel Angel, Farr, Carol L., Kaguni, Laurie S., Garesse, Rafael
Gepubliceerd in Methods Mol Biol (2007)

The accessory subunit of DNA polymerase γ is essential for mitochondrial DNA maintenance and development in Drosophila melanogaster

door Iyengar, Balaji, Luo, Ningguang, Farr, Carol L., Kaguni, Laurie S., Campos, Ana Regina
Gepubliceerd in 2002

Functional analysis of H. sapiens DNA polymerase γ spacer mutation W748S with and without common variant E1143G

door Palin, Eino JH, Lesonen, Annamari, Farr, Carol L, Euro, Liliya, Suomalainen, Anu, Kaguni, Laurie S
Gepubliceerd in 2010

MUSCLE-SPECIFIC OVEREXPRESSION OF THE CATALYTIC SUBUNIT OF DNA POLYMERASE γ INDUCES PUPAL LETHALITY IN Drosophila melanogaster

door Martínez-Azorín, Francisco, Calleja, Manuel, Hernández-Sierra, Rosana, Farr, Carol L., Kaguni, Laurie S., Garesse, Rafael
Gepubliceerd in Arch Insect Biochem Physiol (2013)

Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion

door Martínez-Azorín, Francisco, Calleja, Manuel, Hernández-Sierra, Rosana, Farr, Carol L., Kaguni, Laurie S., Garesse, Rafael
Gepubliceerd in J Neurochem (2007)

Mitochondrial Single-stranded DNA-binding Protein Is Required for Mitochondrial DNA Replication and Development in Drosophila melanogaster

door Maier, Dieter, Farr, Carol L., Poeck, Burkhard, Alahari, Anuradha, Vogel, Marion, Fischer, Susanne, Kaguni, Laurie S., Schneuwly, Stephan
Gepubliceerd in 2001

A Novel Processive Mechanism for DNA Synthesis Revealed by Structure, Modeling and Mutagenesis of the Accessory Subunit of Human Mitochondrial DNA Polymerase

door Fan, Li, Kim, Sangbumn, Farr, Carol L., Schaefer, Kevin T., Randolph, Kathleen M., Tainer, John A., Kaguni, Laurie S.
Gepubliceerd in J Mol Biol (2006)

Structural and Functional Characterization of BaiA, An Enzyme Involved in Secondary Bile Acid Synthesis in Human Gut Microbe

door Bhowmik, Shiva, Jones, David H., Chiu, Hsien-Po, Park, In-Hee, Chiu, Hsiu-Ju, Axelrod, Herbert L., Farr, Carol L., Tien, Henry J., Agarwalla, Sanjay, Lesley, Scott A.
Gepubliceerd in 2013

Structures of a bifunctional cell-wall hydrolase CwlT containing a novel bacterial lysozyme and an NlpC/P60 dl-endopeptidase

door Xu, Qingping, Chiu, Hsiu-Ju, Farr, Carol L., Jaroszewski, Lukasz, Knuth, Mark W., Miller, Mitchell D., Lesley, Scott A., Godzik, Adam, Elsliger, Marc-André, Deacon, Ashley M., Wilson, Ian A.
Gepubliceerd in 2013

Structural analysis of arabinose-5-phosphate isomerase from Bacteroides fragilis and functional implications

door Chiu, Hsiu-Ju, Grant, Joanna C., Farr, Carol L., Jaroszewski, Lukasz, Knuth, Mark W., Miller, Mitchell D., Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Gepubliceerd in 2014

Crystal structure of a member of a novel family of dioxygenases (PF10014) reveals a conserved cupin fold and active site

door Xu, Qingping, Grant, Joanna, Chiu, Hsiu-Ju, Farr, Carol L., Jaroszewski, Lukasz, Knuth, Mark W., Miller, Mitchell D., Lesley, Scott A., Godzik, Adam, Elsliger, Marc-André, Deacon, Ashley M., Wilson, Ian A.
Gepubliceerd in 2013

Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family

door Das, Debanu, Chiu, Hsiu-Ju, Farr, Carol L., Grant, Joanna C., Jaroszewski, Lukasz, Knuth, Mark W., Miller, Mitchell D., Tien, Henry J., Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Gepubliceerd in 2013

Structure and Functional Characterization of a Bile Acid 7α Dehydratase BaiE in Secondary Bile Acid Synthesis

door Bhowmik, Shiva, Chiu, Hsien-Po, Jones, David H., Chiu, Hsiu-Ju, Miller, Mitchell D., Xu, Qingping, Farr, Carol L., Ridlon, Jason M., Wells, James E., Elsliger, Marc-André, Wilson, Ian A., Hylemon, Phillip B., Lesley, Scott A.
Gepubliceerd in Proteins (2016)

Structure and Function of the First Full-Length Murein Peptide Ligase (Mpl) Cell Wall Recycling Protein

door Das, Debanu, Hervé, Mireille, Feuerhelm, Julie, Farr, Carol L., Chiu, Hsiu-Ju, Elsliger, Marc-André, Knuth, Mark W., Klock, Heath E., Miller, Mitchell D., Godzik, Adam, Lesley, Scott A., Deacon, Ashley M., Mengin-Lecreulx, Dominique, Wilson, Ian A.
Gepubliceerd in 2011

Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains

door Xu, Qingping, Mengin-Lecreulx, Dominique, Liu, Xueqian W., Patin, Delphine, Farr, Carol L., Grant, Joanna C., Chiu, Hsiu-Ju, Jaroszewski, Lukasz, Knuth, Mark W., Godzik, Adam, Lesley, Scott A., Elsliger, Marc-André, Deacon, Ashley M., Wilson, Ian A.
Gepubliceerd in mBio (2015)

Structural and Sequence Analysis of Imelysin-Like Proteins Implicated in Bacterial Iron Uptake

door Xu, Qingping, Rawlings, Neil D., Farr, Carol L., Chiu, Hsiu-Ju, Grant, Joanna C., Jaroszewski, Lukasz, Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Weekes, Dana, Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Gepubliceerd in 2011

Structure and Function of the DUF2233 Domain in Bacteria and in the Human Mannose 6-Phosphate Uncovering Enzyme

door Das, Debanu, Lee, Wang-Sik, Grant, Joanna C., Chiu, Hsiu-Ju, Farr, Carol L., Vance, Julie, Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Kornfeld, Stuart, Wilson, Ian A.
Gepubliceerd in 2013

Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake

door Kumar, Abhinav, Punta, Marco, Axelrod, Herbert L, Das, Debanu, Farr, Carol L, Grant, Joanna C, Chiu, Hsiu-Ju, Miller, Mitchell D, Coggill, Penelope C, Klock, Heath E, Elsliger, Marc-André, Deacon, Ashley M, Godzik, Adam, Lesley, Scott A, Wilson, Ian A
Gepubliceerd in Protein Sci (2014)