Insights into Substrate Specificity of NlpC/P60 Cell Wall Hydrolases Containing Bacterial SH3 Domains

Bacterial SH3 (SH3b) domains are commonly fused with papain-like Nlp/P60 cell wall hydrolase domains. To understand how the modular architecture of SH3b and NlpC/P60 affects the activity of the catalytic domain, three putative NlpC/P60 cell wall hydrolases were biochemically and structurally charact...

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Veröffentlicht in:mBio
Hauptverfasser: Xu, Qingping, Mengin-Lecreulx, Dominique, Liu, Xueqian W., Patin, Delphine, Farr, Carol L., Grant, Joanna C., Chiu, Hsiu-Ju, Jaroszewski, Lukasz, Knuth, Mark W., Godzik, Adam, Lesley, Scott A., Elsliger, Marc-André, Deacon, Ashley M., Wilson, Ian A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Microbiology 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600125/
https://ncbi.nlm.nih.gov/pubmed/26374125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02327-14
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