Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites

NlpC/P60 superfamily papain-like enzymes play important roles in all kingdoms of life. Two members of this superfamily, LRAT-like and YaeF/YiiX-like families, were predicted to contain a catalytic domain that is circularly permuted such that the catalytic cysteine is located near the C-terminus, ins...

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Detalhes bibliográficos
Main Authors: Xu, Qingping, Rawlings, Neil D., Chiu, Hsiu-Ju, Jaroszewski, Lukasz, Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Elsliger, Marc-Andre, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142127/
https://ncbi.nlm.nih.gov/pubmed/21799766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022013
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