Animal models of mitochondrial DNA transactions in disease and ageing

Por Oliveira, Marcos T., Garesse, Rafael, Kaguni, Laurie S.
Publicado em 2010

Functional Analysis by Inducible RNA Interference in Drosophila melanogaster

Por Matsushima, Yuichi, Adán, Cristina, Garesse, Rafael, Kaguni, Laurie S.
Publicado no Methods Mol Biol (2007)

Drosophila melanogaster as a Model System to Study Mitochondrial Biology

Por Fernández-Moreno, Miguel Angel, Farr, Carol L., Kaguni, Laurie S., Garesse, Rafael
Publicado no Methods Mol Biol (2007)

Co-occurrence of four nucleotide changes associated with an adult mitochondrial ataxia phenotype

Por Zabalza, Ramón, Nurminen, Anssi, Kaguni, Laurie S, Garesse, Rafael, Gallardo, M Esther, Bornstein, Belén
Publicado no BMC Res Notes (2014)

The pathogenicity scoring system for mitochondrial tRNA mutations revisited

Por González-Vioque, Emiliano, Bornstein, Belén, Gallardo, María Esther, Fernández-Moreno, Miguel Ángel, Garesse, Rafael
Publicado em 2014

MUSCLE-SPECIFIC OVEREXPRESSION OF THE CATALYTIC SUBUNIT OF DNA POLYMERASE γ INDUCES PUPAL LETHALITY IN Drosophila melanogaster

Por Martínez-Azorín, Francisco, Calleja, Manuel, Hernández-Sierra, Rosana, Farr, Carol L., Kaguni, Laurie S., Garesse, Rafael
Publicado no Arch Insect Biochem Physiol (2013)

Over-expression of the catalytic core of mitochondrial DNA (mtDNA) polymerase in the nervous system of Drosophila melanogaster reduces median life span by inducing mtDNA depletion

Por Martínez-Azorín, Francisco, Calleja, Manuel, Hernández-Sierra, Rosana, Farr, Carol L., Kaguni, Laurie S., Garesse, Rafael
Publicado no J Neurochem (2007)

Modeling Pathogenic Mutations of Human Twinkle in Drosophila Suggests an Apoptosis Role in Response to Mitochondrial Defects

Por Sanchez-Martinez, Alvaro, Calleja, Manuel, Peralta, Susana, Matsushima, Yuichi, Hernandez-Sierra, Rosana, Whitworth, Alexander J., Kaguni, Laurie S., Garesse, Rafael
Publicado em 2012

hCOA3 Stabilizes Cytochrome c Oxidase 1 (COX1) and Promotes Cytochrome c Oxidase Assembly in Human Mitochondria

Por Clemente, Paula, Peralta, Susana, Cruz-Bermudez, Alberto, Echevarría, Lucía, Fontanesi, Flavia, Barrientos, Antoni, Fernandez-Moreno, Miguel A., Garesse, Rafael
Publicado em 2013

Generating Rho-0 Cells Using Mesenchymal Stem Cell Lines

Por Fernández-Moreno, Mercedes, Hermida-Gómez, Tamara, Gallardo, M. Esther, Dalmao-Fernández, Andrea, Rego-Pérez, Ignacio, Garesse, Rafael, Blanco, Francisco J.
Publicado no PLoS One (2016)

Enhanced tumorigenicity by mitochondrial DNA mild mutations

Por Cruz-Bermúdez, Alberto, Vallejo, Carmen G., Vicente-Blanco, Ramiro J., Gallardo, María Esther, Fernández-Moreno, Miguel Ángel, Quintanilla, Miguel, Garesse, Rafael
Publicado no Oncotarget (2015)

Modeling human mitochondrial diseases in flies

Por Sánchez-Martínez, Álvaro, Luo, Ningguang, Clemente, Paula, Adán, Cristina, Hernández-Sierra, Rosana, Ochoa, Pilar, Fernández-Moreno, Miguel Ángel, Kaguni, Laurie S., Garesse, Rafael
Publicado no Biochim Biophys Acta (2006)

Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model

Por Martínez-Morentin, Leticia, Martínez, Lidia, Piloto, Sarah, Yang, Hua, Schon, Eric A., Garesse, Rafael, Bodmer, Rolf, Ocorr, Karen, Cervera, Margarita, Arredondo, Juan J.
Publicado no Hum Mol Genet (2015)

Drosophila nuclear factor DREF regulates the expression of the mitochondrial DNA helicase and mitochondrial transcription factor B2 but not the mitochondrial translation factor B1

Por Fernández-Moreno, Miguel A., Hernández, Rosana, Adán, Cristina, Roberti, Marina, Bruni, Francesco, Polosa, Paola Loguercio, Cantatore, Palmiro, Matsushima, Yuichi, Kaguni, Laurie S., Garesse, Rafael
Publicado no Biochim Biophys Acta (2013)

The thyroid hormone receptor β induces DNA damage and premature senescence

Por Zambrano, Alberto, García-Carpizo, Verónica, Gallardo, María Esther, Villamuera, Raquel, Gómez-Ferrería, Maria Ana, Pascual, Angel, Buisine, Nicolas, Sachs, Laurent M., Garesse, Rafael, Aranda, Ana
Publicado em 2014

Mitochondrial Transcription Factor B2 Is Essential for Metabolic Function in Drosophila melanogaster Development

Por Adán, Cristina, Matsushima, Yuichi, Hernández-Sierra, Rosana, Marco-Ferreres, Raquel, Fernández-Moreno, Miguel Ángel, González-Vioque, Emiliano, Calleja, Manuel, Aragón, Juan J., Kaguni, Laurie S., Garesse, Rafael
Publicado em 2008

Coiled Coil Domain-containing Protein 56 (CCDC56) Is a Novel Mitochondrial Protein Essential for Cytochrome c Oxidase Function

Por Peralta, Susana, Clemente, Paula, Sánchez-Martínez, Álvaro, Calleja, Manuel, Hernández-Sierra, Rosana, Matsushima, Yuichi, Adán, Cristina, Ugalde, Cristina, Fernández-Moreno, Miguel Ángel, Kaguni, Laurie S., Garesse, Rafael
Publicado em 2012

Functional Characterization of Three Concomitant MtDNA LHON Mutations Shows No Synergistic Effect on Mitochondrial Activity

Por Cruz-Bermúdez, Alberto, Vicente-Blanco, Ramiro J., Hernández-Sierra, Rosana, Montero, Mayte, Alvarez, Javier, González Manrique, Mar, Blázquez, Alberto, Martín, Miguel Angel, Ayuso, Carmen, Garesse, Rafael, Fernández-Moreno, Miguel A.
Publicado no PLoS One (2016)

Comparative analysis of the pathogenic mechanisms associated with the G8363A and A8296G mutations in the mitochondrial tRNA(Lys) gene

Por Bornstein, Belén, Mas, José Antonio, Patrono, Clarice, Fernández-Moreno, Miguel Angel, González-Vioque, Emiliano, Campos, Yolanda, Carrozzo, Rosalba, Martín, Miguel Angel, Hoyo, Pilar del, Santorelli, Filippo M., Arenas, Joaquín, Garesse, Rafael
Publicado em 2005

Reactive oxygen species mediate the down-regulation of mitochondrial transcripts and proteins by tumour necrosis factor-alpha in L929 cells.

Por Sánchez-Alcázar, José A, Schneider, Erasmus, Hernández-Muñoz, Inmaculada, Ruiz-Cabello, Jesús, Siles-Rivas, Eva, de la Torre, Paz, Bornstein, Belen, Brea, Gloria, Arenas, Joaquín, Garesse, Rafael, Solís-Herruzo, José A, Knox, Alan J, Navas, Plácido
Publicado em 2003