Mitochondrial transcription: Lessons from mouse models

Por Peralta, Susana, Wang, Xiao, Moraes, Carlos T.
Publicado em 2011

MITOCHONDRIAL DISEASES PART I: MOUSE MODELS OF OXPHOS DEFICIENCIES CAUSED BY DEFECTS ON RESPIRATORY COMPLEX SUBUNITS OR ASSEMBLY FACTORS

Por Torraco, Alessandra, Peralta, Susana, Iommarini, Luisa, Diaz, Francisca
Publicado no Mitochondrion (2015)

MITOCHONDRIAL DISEASES PART II: MOUSE MODELS OF OXPHOS DEFICIENCIES CAUSED BY DEFECTS IN REGULATORY FACTORS AND OTHER COMPONENTS REQUIRED FOR MITOCHONDRIAL FUNCTION

Por Iommarini, Luisa, Peralta, Susana, Torraco, Alessandra, Diaz, Francisca
Publicado no Mitochondrion (2015)

MITOCHONDRIAL DISEASES PART III: THERAPEUTIC INTERVENTIONS IN MOUSE MODELS OF OXPHOS DEFICIENCIES

Por Peralta, Susana, Torraco, Alessandra, Iommarini, Luisa, Diaz, Francisca
Publicado no Mitochondrion (2015)

Partial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage

Por Peralta, Susana, Torraco, Alessandra, Wenz, Tina, Garcia, Sofia, Diaz, Francisca, Moraes, Carlos T.
Publicado em 2014

Specific elimination of mutant mitochondrial genomes in patient–derived cells by mitoTALENs

Por Bacman, Sandra R., Williams, Siôn L., Pinto, Milena, Peralta, Susana, Moraes, Carlos T.
Publicado em 2013

Pioglitazone ameliorates the phenotype of a novel Parkinson’s disease mouse model by reducing neuroinflammation

Por Pinto, Milena, Nissanka, Nadee, Peralta, Susana, Brambilla, Roberta, Diaz, Francisca, Moraes, Carlos T.
Publicado no Mol Neurodegener (2016)

Sustained AMPK activation improves muscle function in a mitochondrial myopathy mouse model by promoting muscle fiber regeneration

Por Peralta, Susana, Garcia, Sofia, Yin, Han Yang, Arguello, Tania, Diaz, Francisca, Moraes, Carlos T.
Publicado no Hum Mol Genet (2016)

Modeling Pathogenic Mutations of Human Twinkle in Drosophila Suggests an Apoptosis Role in Response to Mitochondrial Defects

Por Sanchez-Martinez, Alvaro, Calleja, Manuel, Peralta, Susana, Matsushima, Yuichi, Hernandez-Sierra, Rosana, Whitworth, Alexander J., Kaguni, Laurie S., Garesse, Rafael
Publicado em 2012

hCOA3 Stabilizes Cytochrome c Oxidase 1 (COX1) and Promotes Cytochrome c Oxidase Assembly in Human Mitochondria

Por Clemente, Paula, Peralta, Susana, Cruz-Bermudez, Alberto, Echevarría, Lucía, Fontanesi, Flavia, Barrientos, Antoni, Fernandez-Moreno, Miguel A., Garesse, Rafael
Publicado em 2013

MitoTALEN: A General Approach to Reduce Mutant mtDNA Loads and Restore Oxidative Phosphorylation Function in Mitochondrial Diseases

Por Hashimoto, Masami, Bacman, Sandra R, Peralta, Susana, Falk, Marni J, Chomyn, Anne, Chan, David C, Williams, Sion L, Moraes, Carlos T
Publicado no Mol Ther (2015)

ATAD3 controls mitochondrial cristae structure in mouse muscle, influencing mtDNA replication and cholesterol levels

Por Peralta, Susana, Goffart, Steffi, Williams, Sion L., Diaz, Francisca, Garcia, Sofia, Nissanka, Nadee, Area-Gomez, Estela, Pohjoismäki, Jaakko, Moraes, Carlos T.
Publicado no J Cell Sci (2018)

Overexpression of PGC‐1α in aging muscle enhances a subset of young‐like molecular patterns

Por Garcia, Sofia, Nissanka, Nadee, Mareco, Edson A., Rossi, Susana, Peralta, Susana, Diaz, Francisca, Rotundo, Richard L., Carvalho, Robson F., Moraes, Carlos T.
Publicado no Aging Cell (2018)

Coiled Coil Domain-containing Protein 56 (CCDC56) Is a Novel Mitochondrial Protein Essential for Cytochrome c Oxidase Function

Por Peralta, Susana, Clemente, Paula, Sánchez-Martínez, Álvaro, Calleja, Manuel, Hernández-Sierra, Rosana, Matsushima, Yuichi, Adán, Cristina, Ugalde, Cristina, Fernández-Moreno, Miguel Ángel, Kaguni, Laurie S., Garesse, Rafael
Publicado em 2012