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Overexpression of PGC‐1α in aging muscle enhances a subset of young‐like molecular patterns
PGC‐1α is a transcriptional co‐activator known as the master regulator of mitochondrial biogenesis. Its control of metabolism has been suggested to exert critical influence in the aging process. We have aged mice overexpressing PGC‐1α in skeletal muscle to determine whether the transcriptional chang...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5847875/ https://ncbi.nlm.nih.gov/pubmed/29427317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12707 |
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