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Overexpression of PGC‐1α in aging muscle enhances a subset of young‐like molecular patterns
PGC‐1α is a transcriptional co‐activator known as the master regulator of mitochondrial biogenesis. Its control of metabolism has been suggested to exert critical influence in the aging process. We have aged mice overexpressing PGC‐1α in skeletal muscle to determine whether the transcriptional chang...
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| Udgivet i: | Aging Cell |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5847875/ https://ncbi.nlm.nih.gov/pubmed/29427317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12707 |
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