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Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging

Aging is a major risk factor for metabolic disease and loss of skeletal muscle mass and strength, a condition known as sarcopenia. Both conditions present a major health burden to the elderly population. Here, we analyzed the effect of mildly increased PGC-1α expression in skeletal muscle during agi...

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Detalhes bibliográficos
Main Authors: Wenz, Tina, Rossi, Susana G., Rotundo, Richard L., Spiegelman, Bruce M., Moraes, Carlos T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787152/
https://ncbi.nlm.nih.gov/pubmed/19918075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911570106
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