Structure and Function of the DUF2233 Domain in Bacteria and in the Human Mannose 6-Phosphate Uncovering Enzyme

DUF2233, a domain of unknown function (DUF), is present in many bacterial and several viral proteins and was also identified in the mammalian transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester α-N-acetylglucosaminidase (“uncovering enzyme” (UCE)). We report the crystal structure of BACO...

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Main Authors: Das, Debanu, Lee, Wang-Sik, Grant, Joanna C., Chiu, Hsiu-Ju, Farr, Carol L., Vance, Julie, Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Kornfeld, Stuart, Wilson, Ian A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Protein Structure and Folding
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675612/
https://ncbi.nlm.nih.gov/pubmed/23572527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.434977
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