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Physiological and Biochemical Defects in Carboxyl-terminal Mutants of Mitochondrial DNA Helicase
Mitochondrial DNA helicase, also called Twinkle, is essential for mtDNA maintenance. Its helicase domain shares high homology with helicases from superfamily 4. Structural analyses of helicases from this family indicate that carboxyl-terminal residues contribute to NTP hydrolysis required for transl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527111/ https://ncbi.nlm.nih.gov/pubmed/18593709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803674200 |
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