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The N-terminal Domain of the Drosophila Mitochondrial Replicative DNA Helicase Contains an Iron-Sulfur Cluster and Binds DNA

The metazoan mitochondrial DNA helicase is an integral part of the minimal mitochondrial replisome. It exhibits strong sequence homology with the bacteriophage T7 gene 4 protein primase-helicase (T7 gp4). Both proteins contain distinct N- and C-terminal domains separated by a flexible linker. The C-...

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Detalhes bibliográficos
Main Authors: Stiban, Johnny, Farnum, Gregory A., Hovde, Stacy L., Kaguni, Laurie S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4148837/
https://ncbi.nlm.nih.gov/pubmed/25023283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587774
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