Specialization among Iron-Sulfur Cluster Helicases to Resolve G-quadruplex DNA Structures That Threaten Genomic Stability

G-quadruplex (G4) DNA, an alternate structure formed by Hoogsteen hydrogen bonds between guanines in G-rich sequences, threatens genomic stability by perturbing normal DNA transactions including replication, repair, and transcription. A variety of G4 topologies (intra- and intermolecular) can form i...

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Hlavní autoři: Bharti, Sanjay Kumar, Sommers, Joshua A., George, Fourbears, Kuper, Jochen, Hamon, Florian, Shin-ya, Kazuo, Teulade-Fichou, Marie-Paule, Kisker, Caroline, Brosh, Robert M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2013
Témata:
DNA and Chromosomes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784731/
https://ncbi.nlm.nih.gov/pubmed/23935105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.496463
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