Impact of Age-Associated Cyclopurine Lesions on DNA Repair Helicases

8,5′ cyclopurine deoxynucleosides (cPu) are locally distorting DNA base lesions corrected by nucleotide excision repair (NER) and proposed to play a role in neurodegeneration prevalent in genetically defined Xeroderma pigmentosum (XP) patients. In the current study, purified recombinant helicases fr...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Khan, Irfan, Suhasini, Avvaru N., Banerjee, Taraswi, Sommers, Joshua A., Kaplan, Daniel L., Kuper, Jochen, Kisker, Caroline, Brosh, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237422/
https://ncbi.nlm.nih.gov/pubmed/25409515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113293
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