Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

le Cassady, John P., D’Alessio, Ana C., Sarkar, Sovan, Dani, Vardhan S., Fan, Zi Peng, Ganz, Kibibi, Roessler, Reinhard, Sur, Mriganka, Young, Richard A., Jaenisch, Rudolf
Foilsithe in Stem Cell Reports (2014)

Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes

le Dowen, Jill M., Fan, Zi Peng, Hnisz, Denes, Ren, Gang, Abraham, Brian J., Zhang, Lyndon N., Weintraub, Abraham S., Schujiers, Jurian, Lee, Tong Ihn, Zhao, Keji, Young, Richard A.
Foilsithe 2014

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

le Signer, Robert A.J., Qi, Le, Zhao, Zhiyu, Thompson, David, Sigova, Alla A., Fan, Zi Peng, DeMartino, George N., Young, Richard A., Sonenberg, Nahum, Morrison, Sean J.
Foilsithe in Genes Dev (2016)

3D chromosome regulatory landscape of human pluripotent cells

le Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.
Foilsithe in Cell Stem Cell (2015)

Genome-wide determination of drug localization

le Anders, Lars, Guenther, Matthew G., Qi, Jun, Fan, Zi Peng, Marineau, Jason J., Rahl, Peter B., Lovén, Jakob, Sigova, Alla A., Smith, William B., Lee, Tong Ihn, Bradner, James E., Young, Richard A.
Foilsithe 2013

Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

le Xu, Cong, Fan, Zi Peng, Müller, Patrick, Fogley, Rachel, DiBiase, Anthony, Trompouki, Eirini, Unternaehrer, Juli, Xiong, Fengzhu, Torregroza, Ingrid, Evans, Todd, Megason, Sean G., Daley, George Q., Schier, Alexander F., Young, Richard A., Zon, Leonard I.
Foilsithe 2012

Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T-cell Acute Lymphoblastic Leukemia

le Sanda, Takaomi, Lawton, Lee N., Barrasa, M. Inmaculada, Fan, Zi Peng, Kohlhammer, Holger, Gutierrez, Alejandro, Ma, Wenxue, Tatarek, Jessica, Ahn, Yebin, Kelliher, Michelle A., Jamieson, Catriona H. M., Staudt, Louis M., Young, Richard A., Look, A. Thomas
Foilsithe 2012

A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity

le D’Alessio, Ana C., Fan, Zi Peng, Wert, Katherine J., Baranov, Petr, Cohen, Malkiel A., Saini, Janmeet S., Cohick, Evan, Charniga, Carol, Dadon, Daniel, Hannett, Nancy M., Young, Michael J., Temple, Sally, Jaenisch, Rudolf, Lee, Tong Ihn, Young, Richard A.
Foilsithe in Stem Cell Reports (2015)

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

le Kaufman, Charles K., Mosimann, Christian, Fan, Zi Peng, Yang, Song, Thomas, Andrew, Ablain, Julien, Tan, Justin L., Fogley, Rachel D., van Rooijen, Ellen, Hagedorn, Elliott, Ciarlo, Christie, White, Richard, Matos, Dominick, Puller, Ann-Christin, Santoriello, Cristina, Liao, Eric, Young, Richard A., Zon, Leonard I.
Foilsithe in Science (2016)

Activation of proto-oncogenes by disruption of chromosome neighborhoods

le Hnisz, Denes, Weintraub, Abraham S., Day, Daniel S., Valton, Anne-Laure, Bak, Rasmus O., Li, Charles H., Goldmann, Johanna, Lajoie, Bryan R., Fan, Zi Peng, Sigova, Alla A., Reddy, Jessica, Borges-Rivera, Diego, Lee, Tong Ihn, Jaenisch, Rudolf, Porteus, Matthew H., Dekker, Job, Young, Richard A.
Foilsithe in Science (2016)

Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration

le Trompouki, Eirini, Bowman, Teresa V., Lawton, Lee N., Fan, Zi Peng, Wu, Dai-Chen, DiBiase, Anthony, Martin, Corey S., Cech, Jennifer N., Sessa, Anna K., Leblanc, Jocelyn L., Li, Pulin, Durand, Ellen, Mosimann, Christian, Heffner, Garrett C., Daley, George Q., Paulson, Robert F., Young, Richard A., Zon, Leonard I.
Foilsithe 2011

Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation

le Frumm, Stacey M., Fan, Zi Peng, Ross, Kenneth N., Duvall, Jeremy R., Gupta, Supriya, VerPlank, Lynn, Suh, Byung-Chul, Holson, Edward, Wagner, Florence F., Smith, William B., Paranal, Ronald M., Bassil, Christopher F., Qi, Jun, Roti, Giovanni, Kung, Andrew L., Bradner, James E., Tolliday, Nicola, Stegmaier, Kimberly
Foilsithe 2013

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

le Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Foilsithe 2014

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

le Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Foilsithe in Cell Stem Cell (2014)

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

le Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Foilsithe in Cell Stem Cell (2014)

A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition

le Mahoney, Christopher E., Pirman, David, Chubukov, Victor, Sleger, Taryn, Hayes, Sebastian, Fan, Zi Peng, Allen, Eric L., Chen, Ying, Huang, Lingling, Liu, Meina, Zhang, Yingjia, McDonald, Gabrielle, Narayanaswamy, Rohini, Choe, Sung, Chen, Yue, Gross, Stefan, Cianchetta, Giovanni, Padyana, Anil K., Murray, Stuart, Liu, Wei, Marks, Kevin M., Murtie, Joshua, Dorsch, Marion, Jin, Shengfang, Nagaraja, Nelamangala, Biller, Scott A., Roddy, Thomas, Popovici-Muller, Janeta, Smolen, Gromoslaw A.
Foilsithe in Nat Commun (2019)

Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma

le Tan, Justin L., Fogley, Rachel D., Flynn, Ryan A., Ablain, Julien, Yang, Song, Saint-André, Violaine, Fan, Zi Peng, Do, Brian T., Laga, Alvaro C., Fujinaga, Koh, Santoriello, Cristina, Greer, Celeste B., Kim, Yoon Jung, Clohessy, John G., Bothmer, Anne, Pandell, Nicole, Avagyan, Serine, Brogie, John E., van Rooijen, Ellen, Hagedorn, Elliott J., Shyh-Chang, Ng, White, Richard M., Price, David H., Pandolfi, Pier Paolo, Peterlin, B. Matija, Zhou, Yi, Kim, Tae Hoon, Asara, John M., Chang, Howard Y., Young, Richard A., Zon, Leonard I.
Foilsithe in Mol Cell (2016)