Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation

While cytotoxic chemotherapy remains the hallmark of cancer treatment, intensive regimens fall short in many malignancies, including high-risk neuroblastoma. One alternative strategy is to therapeutically promote tumor differentiation. We created a gene expression signature to measure neuroblast mat...

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Detalhes bibliográficos
Main Authors: Frumm, Stacey M., Fan, Zi Peng, Ross, Kenneth N., Duvall, Jeremy R., Gupta, Supriya, VerPlank, Lynn, Suh, Byung-Chul, Holson, Edward, Wagner, Florence F., Smith, William B., Paranal, Ronald M., Bassil, Christopher F., Qi, Jun, Roti, Giovanni, Kung, Andrew L., Bradner, James E., Tolliday, Nicola, Stegmaier, Kimberly
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3919449/
https://ncbi.nlm.nih.gov/pubmed/23706636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.03.020
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