Direct Evidence for a Critical Role of Myosin II in Budding Yeast Cytokinesis and the Evolvability of New Cytokinetic Mechanisms in the Absence of Myosin II

Por Tolliday, Nicola, Pitcher, Maria, Li, Rong
Publicado em 2003

Characterization of the minimum domain required for targeting budding yeast myosin II to the site of cell division

Por Lister, Ida MB, Tolliday, Nicola J, Li, Rong
Publicado em 2006

Analysis of the Activities of RAD54, a SWI2/SNF2 Protein, Using a Specific Small-molecule Inhibitor

Por Deakyne, Julianna S., Huang, Fei, Negri, Joseph, Tolliday, Nicola, Cocklin, Simon, Mazin, Alexander V.
Publicado em 2013

Screening for Inhibitors of an Essential Chromatin Remodeler in Mouse Embryonic Stem Cells by Monitoring Transcriptional Regulation

Por Dykhuizen, Emily C., Carmody, Leigh C., Tolliday, Nicola, Crabtree, Gerald R., Palmer, Michelle A. J.
Publicado em 2012

Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity

Por Kawasumi, Masaoki, Bradner, James E., Tolliday, Nicola, Thibodeau, Renee, Sloan, Heather, Brummond, Kay M., Nghiem, Paul
Publicado no Cancer Res (2014)

A Chemical Screen Probing the Relationship between Mitochondrial Content and Cell Size

Por Kitami, Toshimori, Logan, David J., Negri, Joseph, Hasaka, Thomas, Tolliday, Nicola J., Carpenter, Anne E., Spiegelman, Bruce M., Mootha, Vamsi K.
Publicado em 2012

Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress

Por Shaw, Alice T., Winslow, Monte M., Magendantz, Margaret, Ouyang, Chensi, Dowdle, James, Subramanian, Aravind, Lewis, Timothy A., Maglathin, Rebecca L., Tolliday, Nicola, Jacks, Tyler
Publicado em 2011

Small molecule inhibitors of HIF-2a translation link its 5’-UTR Iron-Responsive Element (IRE) to oxygen sensing

Por Zimmer, Michael, Ebert, Benjamin L., Neil, Christopher, Brenner, Keith, Papaioannou, Ioannis, Melas, Antonia, Tolliday, Nicola, Lamb, Justin, Pantopoulos, Kostas, Golub, Todd, Iliopoulos, Othon
Publicado em 2008

Protein thermostability above 100°C: A key role for ionic interactions

Por Vetriani, Costantino, Maeder, Dennis L., Tolliday, Nicola, Yip, Kitty S.-P., Stillman, Timothy J., Britton, K. Linda, Rice, David W., Klump, Horst H., Robb, Frank T.
Publicado em 1998

A small-molecule inducer of PDX1 expression identified by high-throughput screening

Por Yuan, Yuan, Hartland, Kate, Boskovic, Zarko, Wang, Yikai, Walpita, Deepika, Lysy, Philippe A., Zhong, Cheng, Young, Damian W., Kim, Young-kwon, Tolliday, Nicola J, Sokal, Etienne M., Schreiber, Stuart L., Wagner, Bridget K.
Publicado em 2013

Cyclin D1-CDK4 Controls Glucose Metabolism Independently of Cell Cycle Progression

Por Lee, Yoonjin, Dominy, John E., Choi, Yoon Jong, Jurczak, Michael, Tolliday, Nicola, Camporez, Joao Paulo, Chim, Helen, Lim, Ji-Hong, Ruan, Hai-Bin, Yang, Xiaoyong, Vazquez, Francisca, Sicinski, Piotr, Shulman, Gerald I., Puigserver, Pere
Publicado em 2014

Selective killing of cancer cells with a small molecule targeting stress response to ROS

Por Raj, Lakshmi, Ide, Takao, Gurkar, Aditi U, Foley, Michael, Schenone, Monica, Li, Xiaoyu, Tolliday, Nicola J., Golub, Todd R., Carr, Steven A., Shamji, Alykhan F., Stern, Andrew M., Mandinova, Anna, Schreiber, Stuart L., Lee, Sam W.
Publicado em 2011

ChemBank: a small-molecule screening and cheminformatics resource database

Por Seiler, Kathleen Petri, George, Gregory A., Happ, Mary Pat, Bodycombe, Nicole E., Carrinski, Hyman A., Norton, Stephanie, Brudz, Steve, Sullivan, John P., Muhlich, Jeremy, Serrano, Martin, Ferraiolo, Paul, Tolliday, Nicola J., Schreiber, Stuart L., Clemons, Paul A.
Publicado em 2008

Identifying the proteins to which small-molecule probes and drugs bind in cells

Por Ong, Shao-En, Schenone, Monica, Margolin, Adam A., Li, Xiaoyu, Do, Kathy, Doud, Mary K., Mani, D. R., Kuai, Letian, Wang, Xiang, Wood, John L., Tolliday, Nicola J., Koehler, Angela N., Marcaurelle, Lisa A., Golub, Todd R., Gould, Robert J., Schreiber, Stuart L., Carr, Steven A.
Publicado em 2009

Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation

Por Frumm, Stacey M., Fan, Zi Peng, Ross, Kenneth N., Duvall, Jeremy R., Gupta, Supriya, VerPlank, Lynn, Suh, Byung-Chul, Holson, Edward, Wagner, Florence F., Smith, William B., Paranal, Ronald M., Bassil, Christopher F., Qi, Jun, Roti, Giovanni, Kung, Andrew L., Bradner, James E., Tolliday, Nicola, Stegmaier, Kimberly
Publicado em 2013

The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia

Por Banerji, Versha, Frumm, Stacey M., Ross, Kenneth N., Li, Loretta S., Schinzel, Anna C., Hahn, Cynthia K., Kakoza, Rose M., Chow, Kwan T., Ross, Linda, Alexe, Gabriela, Tolliday, Nicola, Inguilizian, Haig, Galinsky, Ilene, Stone, Richard M., DeAngelo, Daniel J., Roti, Giovanni, Aster, Jon C., Hahn, William C., Kung, Andrew L., Stegmaier, Kimberly
Publicado em 2012

Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia

Por Gutierrez, Alejandro, Pan, Li, Groen, Richard W.J., Baleydier, Frederic, Kentsis, Alex, Marineau, Jason, Grebliunaite, Ruta, Kozakewich, Elena, Reed, Casie, Pflumio, Francoise, Poglio, Sandrine, Uzan, Benjamin, Clemons, Paul, VerPlank, Lynn, An, Frank, Burbank, Jason, Norton, Stephanie, Tolliday, Nicola, Steen, Hanno, Weng, Andrew P., Yuan, Huipin, Bradner, James E., Mitsiades, Constantine, Look, A. Thomas, Aster, Jon C.
Publicado em 2014

Identification of cancer cytotoxic modulators of PDE3A by predictive chemogenomics

Por de Waal, Luc, Lewis, Timothy A., Rees, Matthew G., Tsherniak, Aviad, Wu, Xiaoyun, Choi, Peter S., Gechijian, Lara, Hartigan, Christina, Faloon, Patrick W., Hickey, Mark J., Tolliday, Nicola, Carr, Steven A., Clemons, Paul A., Munoz, Benito, Wagner, Bridget K., Shamji, Alykhan F., Koehler, Angela N., Schenone, Monica, Burgin, Alex B., Schreiber, Stuart L., Greulich, Heidi, Meyerson, Matthew
Publicado no Nat Chem Biol (2015)

Human Genetics in Rheumatoid Arthritis Guides a High-Throughput Drug Screen of the CD40 Signaling Pathway

Por Li, Gang, Diogo, Dorothée, Wu, Di, Spoonamore, Jim, Dancik, Vlado, Franke, Lude, Kurreeman, Fina, Rossin, Elizabeth J., Duclos, Grant, Hartland, Cathy, Zhou, Xuezhong, Li, Kejie, Liu, Jun, De Jager, Philip L., Siminovitch, Katherine A., Zhernakova, Alexandra, Raychaudhuri, Soumya, Bowes, John, Eyre, Steve, Padyukov, Leonid, Gregersen, Peter K., Worthington, Jane, Gupta, Namrata, Clemons, Paul A., Stahl, Eli, Tolliday, Nicola, Plenge, Robert M.
Publicado em 2013

Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors

Por Chattopadhyay, Shrikanta, Stewart, Alison L., Mukherjee, Siddhartha, Huang, Cherrie, Hartwell, Kimberly A., Miller, Peter G., Subramanian, Radhika, Carmody, Leigh C., Yusuf, Rushdia Z., Sykes, David B., Paulk, Joshiawa, Vetere, Amedeo, Vallet, Sonia, Santo, Loredana, Cirstea, Diana D., Hideshima, Teru, Dančík, Vlado, Majireck, Max M., Hussain, Mahmud M., Singh, Shambhavi, Quiroz, Ryan, Iaconelli, Jonathan, Karmacharya, Rakesh, Tolliday, Nicola J., Clemons, Paul A., Moore, Malcolm A.S., Stern, Andrew M., Shamji, Alykhan F., Ebert, Benjamin L., Golub, Todd R., Raje, Noopur S., Scadden, David T., Schreiber, Stuart L.
Publicado no Cell Rep (2015)