Transcriptional Silencing of the Wnt-Antagonist DKK1 by Promoter Methylation Is Associated with Enhanced Wnt Signaling in Advanced Multiple Myeloma

Yazar: Kocemba, Kinga A., Groen, Richard W. J., van Andel, Harmen, Kersten, Marie José, Mahtouk, Karène, Spaargaren, Marcel, Pals, Steven T.
Baskı/Yayın Bilgisi 2012

Polymeric micelles loaded with carfilzomib increase tolerability in a humanized bone marrow-like scaffold mouse model

Yazar: Varela-Moreira, Aida, van Straten, Demian, van Leur, Heleen F., Ruiter, Ruud W.J., Deshantri, Anil K., Hennink, Wim E., Fens, Marcel H.A.M., Groen, Richard W.J., Schiffelers, Raymond M.
Yayımlandı Int J Pharm X (2020)

Combined CD28 and 4–1BB costimulation potentiates affinity-tuned Chimeric Antigen Receptor-engineered T cells

Yazar: Drent, Esther, Poels, Renée, Ruiter, Ruud, van de Donk, Niels W.C.J., Zweegman, Sonja, Yuan, Huipin, de Bruijn, Joost, Sadelain, Michel, Lokhorst, Henk M., Groen, Richard W.J., Mutis, Tuna, Themeli, Maria
Yayımlandı Clin Cancer Res (2019)

Bone Marrow Mesenchymal Stromal Cell-mediated Resistance in Multiple Myeloma Against NK Cells can be Overcome by Introduction of CD38-CAR or TRAIL-variant

Yazar: Holthof, Lisa C., Stikvoort, Arwen, van der Horst, Hilma J., Gelderloos, Anne T., Poels, Renée, Li, Fengzhi, Groen, Richard W. J., Zweegman, Sonja, van de Donk, Niels W. C. J., O’Dwyer, Michael, Mutis, Tuna
Yayımlandı Hemasphere (2021)

A Rational Strategy for Reducing On-Target Off-Tumor Effects of CD38-Chimeric Antigen Receptors by Affinity Optimization

Yazar: Drent, Esther, Themeli, Maria, Poels, Renée, de Jong-Korlaar, Regina, Yuan, Huipin, de Bruijn, Joost, Martens, Anton C.M., Zweegman, Sonja, van de Donk, Niels W.C.J., Groen, Richard W.J., Lokhorst, Henk M., Mutis, Tuna
Yayımlandı Mol Ther (2017)

N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation

Yazar: Groen, Richard W.J., de Rooij, Martin F.M., Kocemba, Kinga A., Reijmers, Rogier M., de Haan-Kramer, Anneke, Overdijk, Marije B., Aalders, Linda, Rozemuller, Henk, Martens, Anton C.M., Bergsagel, P. Leif, Kersten, Marie José, Pals, Steven T., Spaargaren, Marcel
Baskı/Yayın Bilgisi 2011

CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia

Yazar: Naik, Jyoti, Themeli, Maria, de Jong-Korlaar, Regina, Ruiter, Ruud W.J., Poddighe, Pino J, Yuan, Huipin, de Bruijn, Joost D., Ossenkoppele, Gert J., Zweegman, Sonja, Smit, Linda, Mutis, Tuna, Martens, Anton C.M., van de Donk, Niels W.C.J., Groen, Richard W.J.
Yayımlandı Haematologica (2019)

Sepantronium bromide (YM155) improves daratumumab-mediated cellular lysis of multiple myeloma cells by abrogation of bone marrow stromal cell-induced resistance

Yazar: de Haart, Sanne J., Holthof, Lisa, Noort, Willy A., Minnema, Monique C., Emmelot, Maarten E., Aarts-Riemens, Tineke, Doshi, Parul, Sasser, Kate, Yuan, Huipin, de Bruijn, Joost, Martens, Anton C.M., van de Donk, Niels W.C.J, Lokhorst, Henk M., Groen, Richard W.J., Mutis, Tuna
Yayımlandı Haematologica (2016)

Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

Yazar: Drent, Esther, Groen, Richard W.J., Noort, Willy A., Themeli, Maria, Lammerts van Bueren, Jeroen J., Parren, Paul W.H.I., Kuball, Jürgen, Sebestyen, Zsolt, Yuan, Huipin, de Bruijn, Joost, van de Donk, Niels W.C.J., Martens, Anton C.M., Lokhorst, Henk M., Mutis, Tuna
Yayımlandı Haematologica (2016)

Complete Tumor Regression by Liposomal Bortezomib in a Humanized Mouse Model of Multiple Myeloma

Yazar: Deshantri, Anil K., Fens, Marcel H.A.M., Ruiter, Ruud W.J., Metselaar, Josbert M., Storm, Gert, Mandhane, Sanjay N., Graat, Gerard H.M., Lentjes, Eef G.W., Yuan, Huipin, de Bruijn, Joost D., Mutis, Tuna, Martens, Anton C.M., Groen, Richard W.J., Schiffelers, Raymond M.
Yayımlandı Hemasphere (2020)

Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma

Yazar: Holthof, Lisa C., van der Horst, Hilma J., van Hal-van Veen, Susan E., Ruiter, Ruud W.J., Li, Fengzhi, Buijze, Marijke, Andersen, Morten N., Yuan, Huipin, de Bruijn, Joost, van de Donk, Niels W.C.J., Lokhorst, Henk M., Zweegman, Sonja, Groen, Richard W.J., Mutis, Tuna
Yayımlandı Haematologica (2020)

PHF19 promotes multiple myeloma tumorigenicity through PRC2 activation and broad H3K27me3 domain formation

Yazar: Ren, Zhihong, Ahn, Jeong Hyun, Liu, Hequn, Tsai, Yi-Hsuan, Bhanu, Natarajan V., Koss, Brian, Allison, David F., Ma, Anqi, Storey, Aaron J., Wang, Ping, Mackintosh, Samuel G., Edmondson, Ricky D., Groen, Richard W. J., Martens, Anton C., Garcia, Benjamin A., Tackett, Alan J., Jin, Jian, Cai, Ling, Zheng, Deyou, Wang, Gang Greg
Yayımlandı Blood (2019)

Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia

Yazar: Gutierrez, Alejandro, Pan, Li, Groen, Richard W.J., Baleydier, Frederic, Kentsis, Alex, Marineau, Jason, Grebliunaite, Ruta, Kozakewich, Elena, Reed, Casie, Pflumio, Francoise, Poglio, Sandrine, Uzan, Benjamin, Clemons, Paul, VerPlank, Lynn, An, Frank, Burbank, Jason, Norton, Stephanie, Tolliday, Nicola, Steen, Hanno, Weng, Andrew P., Yuan, Huipin, Bradner, James E., Mitsiades, Constantine, Look, A. Thomas, Aster, Jon C.
Baskı/Yayın Bilgisi 2014

Monocytes and granulocytes reduce CD38 expression levels on myeloma cells in patients treated with daratumumab

Yazar: Krejcik, Jakub, Frerichs, Kris A., Nijhof, Inger S., van Kessel, Berris, van Velzen, Jeroen F., Bloem, Andries C., Broekmans, Marloes E.C., Zweegman, Sonja, van Meerloo, Johan, Musters, René J.P., Poddighe, Pino J., Groen, Richard W.J., Chiu, Christopher, Plesner, Torben, Lokhorst, Henk M., Sasser, A. Kate, Mutis, Tuna, van de Donk, Niels W.C.J.
Yayımlandı Clin Cancer Res (2017)