N-cadherin-mediated interaction with multiple myeloma cells inhibits osteoblast differentiation

BACKGROUND: Multiple myeloma is a hematologic malignancy characterized by a clonal expansion of malignant plasma cells in the bone marrow, which is accompanied by the development of osteolytic lesions and/or diffuse osteopenia. The intricate bi-directional interaction with the bone marrow microenvir...

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Detalhes bibliográficos
Main Authors: Groen, Richard W.J., de Rooij, Martin F.M., Kocemba, Kinga A., Reijmers, Rogier M., de Haan-Kramer, Anneke, Overdijk, Marije B., Aalders, Linda, Rozemuller, Henk, Martens, Anton C.M., Bergsagel, P. Leif, Kersten, Marie José, Pals, Steven T., Spaargaren, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2011
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208683/
https://ncbi.nlm.nih.gov/pubmed/21828122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.038133
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