Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

Adoptive transfer of chimeric antigen receptor-transduced T cells is a promising strategy for cancer immunotherapy. The CD38 molecule, with its high expression on multiple myeloma cells, appears a suitable target for antibody therapy. Prompted by this, we used three different CD38 antibody sequences...

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Bibliografische gegevens
Gepubliceerd in:Haematologica
Hoofdauteurs: Drent, Esther, Groen, Richard W.J., Noort, Willy A., Themeli, Maria, Lammerts van Bueren, Jeroen J., Parren, Paul W.H.I., Kuball, Jürgen, Sebestyen, Zsolt, Yuan, Huipin, de Bruijn, Joost, van de Donk, Niels W.C.J., Martens, Anton C.M., Lokhorst, Henk M., Mutis, Tuna
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Ferrata Storti Foundation 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004365/
https://ncbi.nlm.nih.gov/pubmed/26858358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.137620
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