Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

Adoptive transfer of chimeric antigen receptor-transduced T cells is a promising strategy for cancer immunotherapy. The CD38 molecule, with its high expression on multiple myeloma cells, appears a suitable target for antibody therapy. Prompted by this, we used three different CD38 antibody sequences...

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Publicado en:Haematologica
Main Authors: Drent, Esther, Groen, Richard W.J., Noort, Willy A., Themeli, Maria, Lammerts van Bueren, Jeroen J., Parren, Paul W.H.I., Kuball, Jürgen, Sebestyen, Zsolt, Yuan, Huipin, de Bruijn, Joost, van de Donk, Niels W.C.J., Martens, Anton C.M., Lokhorst, Henk M., Mutis, Tuna
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5004365/
https://ncbi.nlm.nih.gov/pubmed/26858358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.137620
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