Direct Lineage Conversion of Adult Mouse Liver Cells and B Lymphocytes to Neural Stem Cells

Por Cassady, John P., D’Alessio, Ana C., Sarkar, Sovan, Dani, Vardhan S., Fan, Zi Peng, Ganz, Kibibi, Roessler, Reinhard, Sur, Mriganka, Young, Richard A., Jaenisch, Rudolf
Publicado no Stem Cell Reports (2014)

Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes

Por Dowen, Jill M., Fan, Zi Peng, Hnisz, Denes, Ren, Gang, Abraham, Brian J., Zhang, Lyndon N., Weintraub, Abraham S., Schujiers, Jurian, Lee, Tong Ihn, Zhao, Keji, Young, Richard A.
Publicado em 2014

The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs

Por Signer, Robert A.J., Qi, Le, Zhao, Zhiyu, Thompson, David, Sigova, Alla A., Fan, Zi Peng, DeMartino, George N., Young, Richard A., Sonenberg, Nahum, Morrison, Sean J.
Publicado no Genes Dev (2016)

3D chromosome regulatory landscape of human pluripotent cells

Por Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.
Publicado no Cell Stem Cell (2015)

Genome-wide determination of drug localization

Por Anders, Lars, Guenther, Matthew G., Qi, Jun, Fan, Zi Peng, Marineau, Jason J., Rahl, Peter B., Lovén, Jakob, Sigova, Alla A., Smith, William B., Lee, Tong Ihn, Bradner, James E., Young, Richard A.
Publicado em 2013

Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

Por Xu, Cong, Fan, Zi Peng, Müller, Patrick, Fogley, Rachel, DiBiase, Anthony, Trompouki, Eirini, Unternaehrer, Juli, Xiong, Fengzhu, Torregroza, Ingrid, Evans, Todd, Megason, Sean G., Daley, George Q., Schier, Alexander F., Young, Richard A., Zon, Leonard I.
Publicado em 2012

Core Transcriptional Regulatory Circuit Controlled by the TAL1 Complex in Human T-cell Acute Lymphoblastic Leukemia

Por Sanda, Takaomi, Lawton, Lee N., Barrasa, M. Inmaculada, Fan, Zi Peng, Kohlhammer, Holger, Gutierrez, Alejandro, Ma, Wenxue, Tatarek, Jessica, Ahn, Yebin, Kelliher, Michelle A., Jamieson, Catriona H. M., Staudt, Louis M., Young, Richard A., Look, A. Thomas
Publicado em 2012

A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity

Por D’Alessio, Ana C., Fan, Zi Peng, Wert, Katherine J., Baranov, Petr, Cohen, Malkiel A., Saini, Janmeet S., Cohick, Evan, Charniga, Carol, Dadon, Daniel, Hannett, Nancy M., Young, Michael J., Temple, Sally, Jaenisch, Rudolf, Lee, Tong Ihn, Young, Richard A.
Publicado no Stem Cell Reports (2015)

A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation

Por Kaufman, Charles K., Mosimann, Christian, Fan, Zi Peng, Yang, Song, Thomas, Andrew, Ablain, Julien, Tan, Justin L., Fogley, Rachel D., van Rooijen, Ellen, Hagedorn, Elliott, Ciarlo, Christie, White, Richard, Matos, Dominick, Puller, Ann-Christin, Santoriello, Cristina, Liao, Eric, Young, Richard A., Zon, Leonard I.
Publicado no Science (2016)

Activation of proto-oncogenes by disruption of chromosome neighborhoods

Por Hnisz, Denes, Weintraub, Abraham S., Day, Daniel S., Valton, Anne-Laure, Bak, Rasmus O., Li, Charles H., Goldmann, Johanna, Lajoie, Bryan R., Fan, Zi Peng, Sigova, Alla A., Reddy, Jessica, Borges-Rivera, Diego, Lee, Tong Ihn, Jaenisch, Rudolf, Porteus, Matthew H., Dekker, Job, Young, Richard A.
Publicado no Science (2016)

Lineage regulators direct BMP and Wnt pathways to cell-specific programs during differentiation and regeneration

Por Trompouki, Eirini, Bowman, Teresa V., Lawton, Lee N., Fan, Zi Peng, Wu, Dai-Chen, DiBiase, Anthony, Martin, Corey S., Cech, Jennifer N., Sessa, Anna K., Leblanc, Jocelyn L., Li, Pulin, Durand, Ellen, Mosimann, Christian, Heffner, Garrett C., Daley, George Q., Paulson, Robert F., Young, Richard A., Zon, Leonard I.
Publicado em 2011

Selective HDAC1/HDAC2 Inhibitors Induce Neuroblastoma Differentiation

Por Frumm, Stacey M., Fan, Zi Peng, Ross, Kenneth N., Duvall, Jeremy R., Gupta, Supriya, VerPlank, Lynn, Suh, Byung-Chul, Holson, Edward, Wagner, Florence F., Smith, William B., Paranal, Ronald M., Bassil, Christopher F., Qi, Jun, Roti, Giovanni, Kung, Andrew L., Bradner, James E., Tolliday, Nicola, Stegmaier, Kimberly
Publicado em 2013

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

Por Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Publicado em 2014

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

Por Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Publicado no Cell Stem Cell (2014)

Systematic Identification of Culture Conditions for Induction and Maintenance of Naive Human Pluripotency

Por Theunissen, Thorold W., Powell, Benjamin E., Wang, Haoyi, Mitalipova, Maya, Faddah, Dina A., Reddy, Jessica, Fan, Zi Peng, Maetzel, Dorothea, Ganz, Kibibi, Shi, Linyu, Lungjangwa, Tenzin, Imsoonthornruksa, Sumeth, Stelzer, Yonatan, Rangarajan, Sudharshan, D’Alessio, Ana, Zhang, Jianming, Gao, Qing, Dawlaty, Meelad M., Young, Richard A., Gray, Nathanael S., Jaenisch, Rudolf
Publicado no Cell Stem Cell (2014)

A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition

Por Mahoney, Christopher E., Pirman, David, Chubukov, Victor, Sleger, Taryn, Hayes, Sebastian, Fan, Zi Peng, Allen, Eric L., Chen, Ying, Huang, Lingling, Liu, Meina, Zhang, Yingjia, McDonald, Gabrielle, Narayanaswamy, Rohini, Choe, Sung, Chen, Yue, Gross, Stefan, Cianchetta, Giovanni, Padyana, Anil K., Murray, Stuart, Liu, Wei, Marks, Kevin M., Murtie, Joshua, Dorsch, Marion, Jin, Shengfang, Nagaraja, Nelamangala, Biller, Scott A., Roddy, Thomas, Popovici-Muller, Janeta, Smolen, Gromoslaw A.
Publicado no Nat Commun (2019)

Stress from nucleotide depletion activates the transcriptional regulator HEXIM1 to suppress melanoma

Por Tan, Justin L., Fogley, Rachel D., Flynn, Ryan A., Ablain, Julien, Yang, Song, Saint-André, Violaine, Fan, Zi Peng, Do, Brian T., Laga, Alvaro C., Fujinaga, Koh, Santoriello, Cristina, Greer, Celeste B., Kim, Yoon Jung, Clohessy, John G., Bothmer, Anne, Pandell, Nicole, Avagyan, Serine, Brogie, John E., van Rooijen, Ellen, Hagedorn, Elliott J., Shyh-Chang, Ng, White, Richard M., Price, David H., Pandolfi, Pier Paolo, Peterlin, B. Matija, Zhou, Yi, Kim, Tae Hoon, Asara, John M., Chang, Howard Y., Young, Richard A., Zon, Leonard I.
Publicado no Mol Cell (2016)