3D chromosome regulatory landscape of human pluripotent cells

In this study, we describe the 3D regulatory chromosome structural landscape of human naive and primed embryonic stem cells. To devise this map, we identified transcriptional enhancers and insulators in these cells and placed them within the context of cohesin-associated CTCF-CTCF loops using cohesi...

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Publicat a:Cell Stem Cell
Autors principals: Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848748/
https://ncbi.nlm.nih.gov/pubmed/26686465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.11.007
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