3D chromosome regulatory landscape of human pluripotent cells

In this study, we describe the 3D regulatory chromosome structural landscape of human naive and primed embryonic stem cells. To devise this map, we identified transcriptional enhancers and insulators in these cells and placed them within the context of cohesin-associated CTCF-CTCF loops using cohesi...

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Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848748/
https://ncbi.nlm.nih.gov/pubmed/26686465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.11.007
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