3D chromosome regulatory landscape of human pluripotent cells

In this study, we describe the 3D regulatory chromosome structural landscape of human naive and primed embryonic stem cells. To devise this map, we identified transcriptional enhancers and insulators in these cells and placed them within the context of cohesin-associated CTCF-CTCF loops using cohesi...

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Bibliografiske detaljer
Udgivet i:Cell Stem Cell
Main Authors: Ji, Xiong, Dadon, Daniel B., Powell, Benjamin E., Fan, Zi Peng, Borges-Rivera, Diego, Shachar, Sigal, Weintraub, Abraham S., Hnisz, Denes, Pegoraro, Gianluca, Lee, Tong Ihn, Misteli, Tom, Jaenisch, Rudolf, Young, Richard A.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848748/
https://ncbi.nlm.nih.gov/pubmed/26686465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.11.007
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