Nanog-like Regulates Endoderm Formation through the Mxtx2-Nodal Pathway

In mammalian embryonic stem cells, the acquisition of pluripotency is dependent upon Nanog, but the in vivo analysis of Nanog has been hampered by its requirement for early mouse development. In an effort to examine the role of Nanog in vivo, we identified a zebrafish Nanog ortholog, and found that...

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Detalhes bibliográficos
Main Authors: Xu, Cong, Fan, Zi Peng, Müller, Patrick, Fogley, Rachel, DiBiase, Anthony, Trompouki, Eirini, Unternaehrer, Juli, Xiong, Fengzhu, Torregroza, Ingrid, Evans, Todd, Megason, Sean G., Daley, George Q., Schier, Alexander F., Young, Richard A., Zon, Leonard I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3319042/
https://ncbi.nlm.nih.gov/pubmed/22421047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.01.003
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