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Activin/Nodal signalling maintains pluripotency by controlling Nanog expression

The pluripotent status of embryonic stem cells (ESCs) confers upon them the capacity to differentiate into the three primary germ layers, ectoderm, mesoderm and endoderm, from which all the cells of the adult body are derived. An understanding of the mechanisms controlling pluripotency is thus essen...

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Detalhes bibliográficos
Main Authors: Vallier, Ludovic, Mendjan, Sasha, Brown, Stephanie, Chng, Zhenzhi, Teo, Adrian, Smithers, Lucy E., Trotter, Matthew W. B., Cho, Candy H.-H., Martinez, Amelie, Rugg-Gunn, Peter, Brons, Gabrielle, Pedersen, Roger A.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687465/
https://ncbi.nlm.nih.gov/pubmed/19279133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.033951
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