Activin/Nodal signalling maintains pluripotency by controlling Nanog expression

The pluripotent status of embryonic stem cells (ESCs) confers upon them the capacity to differentiate into the three primary germ layers, ectoderm, mesoderm and endoderm, from which all the cells of the adult body are derived. An understanding of the mechanisms controlling pluripotency is thus essen...

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Bibliografische gegevens
Hoofdauteurs: Vallier, Ludovic, Mendjan, Sasha, Brown, Stephanie, Chng, Zhenzhi, Teo, Adrian, Smithers, Lucy E., Trotter, Matthew W. B., Cho, Candy H.-H., Martinez, Amelie, Rugg-Gunn, Peter, Brons, Gabrielle, Pedersen, Roger A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Company of Biologists 2009
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687465/
https://ncbi.nlm.nih.gov/pubmed/19279133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.033951
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