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Inhibition of activin/nodal signalling is necessary for pancreatic differentiation of human pluripotent stem cells

AIMS/HYPOTHESIS: Human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hIPSCs) offer unique opportunities for regenerative medicine and for the study of mammalian development. However, developing methods to differentiate hESCs/hIPSCs into specific cell types following a natura...

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Autores principales: Cho, C. H.-H., Hannan, N. R.-F., Docherty, F. M., Docherty, H. M., Joåo Lima, M., Trotter, M. W. B., Docherty, K., Vallier, L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3483105/
https://ncbi.nlm.nih.gov/pubmed/23011350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2687-x
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