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Pig Epiblast Stem Cells Depend on Activin/Nodal Signaling for Pluripotency and Self-Renewal

Activin/Nodal signaling is required for maintaining pluripotency and self-renewal of mouse epiblast stem cells and human embryonic stem cells (hESC). In this study, we investigated whether this signaling mechanism is also operative in cultured epiblasts derived from Days 10.5–12 pig embryos. Pig epi...

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Detalhes bibliográficos
Main Authors: Alberio, Ramiro, Croxall, Nicola, Allegrucci, Cinzia
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129689/
https://ncbi.nlm.nih.gov/pubmed/20210627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2010.0012
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