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Activin/Nodal signalling maintains pluripotency by controlling Nanog expression

The pluripotent status of embryonic stem cells (ESCs) confers upon them the capacity to differentiate into the three primary germ layers, ectoderm, mesoderm and endoderm, from which all the cells of the adult body are derived. An understanding of the mechanisms controlling pluripotency is thus essen...

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Main Authors: Vallier, Ludovic, Mendjan, Sasha, Brown, Stephanie, Chng, Zhenzhi, Teo, Adrian, Smithers, Lucy E., Trotter, Matthew W. B., Cho, Candy H.-H., Martinez, Amelie, Rugg-Gunn, Peter, Brons, Gabrielle, Pedersen, Roger A.
格式: Artigo
語言:Inglês
出版: Company of Biologists 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687465/
https://ncbi.nlm.nih.gov/pubmed/19279133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.033951
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