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Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes
The pluripotent state of embryonic stem cells (ESCs) is produced by active transcription of genes that control cell identity and repression of genes encoding lineage-specifying developmental regulators. Here we use ESC cohesin ChIAPET data to identify the local chromosomal structures at both active...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4197132/ https://ncbi.nlm.nih.gov/pubmed/25303531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.030 |
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