Deep Amino Acid Sequencing of Native Brain GABA(A) Receptors Using High-Resolution Mass Spectrometry

Por Chen, Zi-Wei, Fuchs, Karoline, Sieghart, Werner, Townsend, R. Reid, Evers, Alex S.
Publicado em 2012

Neuroactive steroids have multiple actions to potentiate GABA(A) receptors

Por Akk, Gustav, Bracamontes, John R, Covey, Douglas F, Evers, Alex, Dao, Tim, Steinbach, Joe Henry
Publicado em 2004

Mechanisms of neurosteroid interactions with GABA(A) receptors

Por Akk, Gustav, Covey, Douglas F., Evers, Alex S., Steinbach, Joe Henry, Zorumski, Charles F., Mennerick, Steven
Publicado em 2007

The influence of the membrane on neurosteroid actions at GABA(A) receptors

Por Akk, Gustav, Covey, Douglas F., Evers, Alex S., Steinbach, Joe Henry, Zorumski, Charles F., Mennerick, Steven
Publicado em 2009

Kinetic and Structural Determinants for GABA-A Receptor Potentiation by Neuroactive Steroids

Por Akk, Gustav, Covey, Douglas F., Evers, Alex S., Mennerick, Steven, Zorumski, Charles F., Steinbach, Joe Henry
Publicado em 2010

Mutational Analysis of the Putative High-Affinity Propofol Binding Site in Human β3 Homomeric GABA(A) Receptors

Por Eaton, Megan M., Cao, Lily Q., Chen, Ziwei, Franks, Nicholas P., Evers, Alex S., Akk, Gustav
Publicado no Mol Pharmacol (2015)

Activation and modulation of recombinant glycine and GABA(A) receptors by 4‐halogenated analogues of propofol

Por Germann, Allison L, Shin, Daniel J, Manion, Brad D, Edge, Christopher J, Smith, Edward H, Franks, Nicholas P, Evers, Alex S, Akk, Gustav
Publicado no Br J Pharmacol (2016)

Neurosteroid Analogues. 15. A Comparative Study of the Anesthetic and GABAergic Actions of Alphaxalone, Δ(16)-Alphaxalone and Their Corresponding 17-Carbonitrile Analogues

Por Bandyopadhyaya, Achintya K., Manion, Brad D., Benz, Ann, Taylor, Amanda, Rath, Nigam P., Evers, Alex S., Zorumski, Charles F., Mennerick, Steven, Covey, Douglas F.
Publicado em 2010

Neurosteroid Analog Photolabeling of a Site in the Third Transmembrane Domain of the β3 Subunit of the GABA(A) Receptor

Por Chen, Zi-Wei, Manion, Brad, Townsend, R. Reid, Reichert, David E., Covey, Douglas F., Steinbach, Joe Henry, Sieghart, Werner, Fuchs, Karoline, Evers, Alex S.
Publicado em 2012

ISOFLURANE-INDUCED NEUROAPOPTOSIS IN THE NEONATAL RHESUS MACAQUE BRAIN

Por Brambrink, Ansgar M., Evers, Alex S., Avidan, Michael S., Farber, Nuri B., Smith, Derek J., Zhang, Xuezhao, Dissen, Gregory A., Creeley, Catherine E., Olney, John W.
Publicado em 2010

Neurosteroid Analogues. 17. Inverted Binding Orientations of Androsterone Enantiomers at the Steroid Potentiation Site on γ-Aminobutyric Acid Type A (GABA(A)) Receptors

Por Krishnan, Kathiresan, Manion, Brad D., Taylor, Amanda, Bracamontes, John, Steinbach, Joseph H., Reichert, David E., Evers, Alex S., Zorumski, Charles F., Mennerick, Steven, Covey, Douglas F.
Publicado em 2012

KETAMINE-INDUCED NEUROAPOPTOSIS IN THE FETAL AND NEONATAL RHESUS MACAQUE BRAIN

Por Brambrink, Ansgar M., Evers, Alex S., Avidan, Michael S., Farber, Nuri B., Smith, Derek J., Martin, Lauren D., Dissen, Gregory A., Creeley, Catherine E., Olney, John W.
Publicado em 2012

Neurosteroid Analogues. 16. A new explanation for the lack of anesthetic effects of Δ(16)-alphaxalone and identification of a Δ(17(20)) analogue with potent anesthetic activity

Por Stastna, Eva, Krishnan, Kathiresan, Manion, Brad D., Taylor, Amanda, Rath, Nigam P., Chen, Zi-Wei, Evers, Alex. S., Zorumski, Charles F., Mennerick, Steven, Covey, Douglas F.
Publicado em 2011

Long-term cognitive decline in older subjects was not attributable to non-cardiac surgery or major illness

Por Avidan, Michael S, FCASA, Searleman, Adam C, Storandt, Martha, Barnett, Kara, Vannucci, Andrea, Saager, Leif, Xiong, Chengjie, Grant, Elizabeth A, Kaiser, Dagmar, Morris, John C, Evers, Alex S
Publicado em 2009

A neurosteroid analogue photolabeling reagent labels the colchicine binding site on tubulin: A mass spectrometric analysis

Por Chen, Zi-Wei, Chen, Li-Hai, Akentieva, Natalia, Lichti, Cheryl F., Darbandi, Ramin, Hastings, Randy, Covey, Douglas F., Reichert, David E., Townsend, R. Reid, Evers, Alex S.
Publicado em 2012

Click chemistry reagent for identification of sites of covalent ligand incorporation in integral membrane proteins

Por Budelier, Melissa M., Cheng, Wayland W. L., Bergdoll, Lucie, Chen, Zi-Wei, Abramson, Jeff, Krishnan, Kathiresan, Qian, Mingxing, Covey, Douglas F., Janetka, James W., Evers, Alex S.
Publicado no Anal Chem (2017)

Relationship between bispectral index values and volatile anesthetic concentrations during the maintenance phase of anesthesia in the B-Unaware trial

Por Whitlock, Elizabeth, Villafranca, Alexander J., Lin, Nan, Palanca, Ben J., Jacobsohn, Eric, Finkel, Kevin J., Zhang, Lini, Burnside, Beth A., Kaiser, Heiko A., Evers, Alex S., Avidan, Michael S.
Publicado em 2011

Neurosteroid Analogues. 18. Structure–Activity Studies of ent-Steroid Potentiators of γ-Aminobutyric Acid type A Receptors and Comparison of Their Activities with Those of Alphaxal...

Por Qian, Mingxing, Krishnan, Kathiresan, Kudova, Eva, Li, Ping, Manion, Brad D., Taylor, Amanda, Elias, George, Akk, Gustav, Evers, Alex S., Zorumski, Charles F., Mennerick, Steven, Covey, Douglas F.
Publicado em 2013

A propofol binding site on mammalian GABA(A) receptors identified by photolabeling

Por Yip, Grace M S, Chen, Zi-Wei, Edge, Christopher J, Smith, Edward H, Dickinson, Robert, Hohenester, Erhard, Townsend, R Reid, Fuchs, Karoline, Sieghart, Werner, Evers, Alex S, Franks, Nicholas P
Publicado em 2013

Photodynamic Effects of Steroid-Conjugated Fluorophores on GABA(A) Receptors

Por Shu, Hong-Jin, Eisenman, Lawrence N., Wang, Cunde, Bandyopadhyaya, Achintya K., Krishnan, Kathiresan, Taylor, Amanda, Benz, Ann M., Manion, Brad, Evers, Alex S., Covey, Douglas F., Zorumski, Charles F., Mennerick, Steven
Publicado em 2009