Activation and modulation of recombinant glycine and GABA(A) receptors by 4‐halogenated analogues of propofol

BACKGROUND AND PURPOSE: Glycine receptors are important players in pain perception and movement disorders and therefore important therapeutic targets. Glycine receptors can be modulated by the intravenous anaesthetic propofol (2,6‐diisopropylphenol). However, the drug is more potent, by at least one...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Germann, Allison L, Shin, Daniel J, Manion, Brad D, Edge, Christopher J, Smith, Edward H, Franks, Nicholas P, Evers, Alex S, Akk, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056230/
https://ncbi.nlm.nih.gov/pubmed/27459129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13566
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